… of assessing and reporting PKPD of anti-tuberculosis drugs when … the extent of the drug
by performing time-kill kinetic studies, … pre-clinical models are useful in the tuberculosis drug …

… In vitro time kill-kinetics assays can be adopted in a predictive preclinical modelling
framework to assess anti-tuberculosis drug activity. This provides important information on the …

… Therefore, as described in this paper, time-kill kinetics assays … The role of the time-kill
kinetics assay as part of a preclinical … of anti-tuberculosis drugs. Tuberculosis (Edinb) 105:80–85. …

… trials that assess the safety, tolerability, drug exposure, and … on preclinical mouse studies
that included pretomanid time-kill and … cell division and mass action kinetics for drug-receptor …

… The role of the time-kill kinetics assay as part of a preclinical modeling framework for
assessing the activity of anti-tuberculosis drugs. Tuberculosis (Edinb) 105:80–85. …

… and verapamil to evaluate their potentiating capacity. … drugs in preclinical models [19,20].
Its capacity to inhibit … at which the time-kill kinetics assays were performed (Section 2.6.). On …

… A study for the investigation of the importance of an in vitro time kill-kinetics assay as an …
preclinical modeling framework evaluating the activity of anti-tuberculosis drugs used this assay. …

… The role of the time-kill kinetics assay as part of a preclinical modeling framework for
assessing the activity of anti-tuberculosis drugs. Tuberculosis. 2017;105:80–5. …

… time-kill assays obtained from high-throughput screening in early discovery are used to
calculate PK-PD target calculations in late preclinical … in vitro assessment of drug activity, since …

… in whole-cell assays to evaluate their activity against the … tuberculosis, or in time-kill curves
to have their mechanism of … in toxicology studies during preclinical development. However, it …